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One of these statements about BSIs is false – which is it?
- The acidic pH of the skin renders it vulnerable to bacterial infection
- The classification of BSIs takes into account whether or not there is extension of infection into the lymphatics and subcutaneous tissue
- The commonest primary BSIs in clinical practice may be due to Staph. aureus, Strep. pyogenes or both
- To avoid increasing emergence of resistant isolates in the community, topical antibiotic therapy should be reserved for mild and very localised BSIs
Which one of these statements about impetigo is false?
- Impetigo usually causes scarring
- The commonest sites of nonbullous impetigo include the face or extremities
- Fusidic acid is the first-line recommended topical agent
- First-line use of mupirocin should be reserved for the treatment of impetigo caused by MRSA
Which one of these statements is false?
- Staph. aureus is the usual cause of folliculitis
- Superficial staphylococcal folliculitis may respond well to simple local antiseptic measures
- Larger furuncles and carbuncles will usually require incision and drainage plus treatment with flucloxacillin
- Severe or recurrent furuncles or carbuncles are commonly due to PVL-associated Staph. aureus in the UK
Regarding cellulitis and erysipelas, which one of these statements is false?
- Cellulitis involves the subcutaneous tissues
- Classical erysipelas has a poorly demarcated border
- Treatment of cellulitis associated with a freshwater- or saltwater-contaminated wound should be discussed with a microbiologist
- Afebrile patients with mild or moderate cellulitis, but no systemic illness or co-morbidity, should be treated with large doses of oral antibiotics
Which one of these statements about topical antibiotics for BSIs is false?
- Fusidic acid is active against most Gram-positive bacteria, but particularly against staphylococci
- Reports of resistance to fusidic acid in the UK have been increasing directly in line with its use topically
- Mupirocin and retapamulin have the same site of action
- The duration of a course of topical treatment with mupirocin should not exceed 10 days
One of these statements about oral antibiotics for BSIs is false – which is it?
- Co-amoxiclav is recommended for first-line therapy for facial cellulitis to cover organisms from the mouth and sinuses
- Flucloxacillin is more active against beta-haemolytic streptococci than penicillin
- Erythromycin is active against staphylococci and streptococci
- Older antibiotics remain the most appropriate antibiotics for treating first episodes of primary community BSIs unless resistance reaches a critical level and is associated with more widespread clinical failures

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