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Which one of these statements about diagnostic criteria for depression is false?
- DSM-IV and ICD-10 do not agree with regard to the range and duration of symptoms
- For a diagnosis of depression, five symptoms are required by DSM-IV and four by ICD-10
- NICE has adopted the DSM-IV criteria
- DSM-IV requires the presence of depressed mood or anhedonia
One of these statements is false - which is it?
- Doctors in primary care do not recognise depression in 50 per cent of individuals with significant depressive symptoms
- Patients in primary care in whom depression is suspected can be screened for depression using two simple questions, which if positive prompt further investigations
- Symptom severity does not influence the choice of treatment
- Patients with suspected depression should be asked directly about suicidal ideation and intent
One of these statements is false - which?
- Antidepressant therapy is recommended for depression of at least moderate severity
- Sertraline is a suitable first-choice antidepressant
- Collaborative care is advocated for individuals with chronic physical conditions who have not responded to either high-intensity psychological treatment, pharmacological treatment or their combination
- Reboxetine should be avoided in patients who experienced sexual dysfunction with other antidepressants
Which one of these statements is false?
- If a patient does not respond to an antidepressant and a dose increase is not effective within four weeks, an alternative antidepressant should be considered
- The likelihood of an adequate treatment response decreases as the number of changes to treatment strategies increases
- Citalopram is a suitable antidepressant for patients with impaired renal function or impaired hepatic function
- Current guidelines emphasise the importance of continuation with antidepressant treatment after symptom remission for at least three months in a first episode of depression
Regarding discontinuing antidepressant therapy, which one of these statements is false?
- The risk of relapse is greatest in the first few months after discontinuation, regardless of duration of treatment
- When discontinuing fluoxetine, the dose should be tapered down over four weeks
- When discontinuing treatment with venlafaxine, the dose should be tapered down over a period of more than four weeks
- The number of previous episodes is one of the factors that should be considered when contemplating discontinuing antidepressant therapy
One of these statements is false - which is it?
- Questionnaires recommended in QOF to assess symptom severity do not correlate well with the HRSD-17
- NICE state that people commencing an antidepressant should normally be reviewed at two- to four-weekly intervals in the first three months and then at longer intervals if response is good
- NICE and the American Psychiatric Association agree that the cut-off point in HRSD-17 that signifies severe depression is a score of 12
- The minimum effective dose of mirtazapine is 30mg daily

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