Escriber.com - Home of Wiley interface

Which one of these statements about the epidemiology of AF is false?
- It affects about 20 per cent of people aged 80 or older
- It appears to be less common among people of Afro-Caribbean or Asian origin than the rest of the population
- It is associated with a five-fold increased risk of embolic stroke
- Strokes associated with AF carry a higher mortality than other strokes
Which of these statements is false?
- AF is associated with common cardiovascular disorders such as hypertension
- AF may be secondary to excessive alcohol consumption
- Myocardial fibrosis promotes the development of arrhythmias
- AF is a rare complication of heart failure
One of these statements about the diagnosis and investigation of AF is false – which is it?
- Holter ECG monitoring is useful in patients with suspected spontaneously cardioverted paroxysmal AF and daily symptoms
- Asymptomatic AF episodes are not uncommon in patients with previous AF paroxysms, who should undergo ECG monitoring
- A transthoracic echocardiogram is seldom useful in the assessment of younger patients
- Renal function should be checked because renal impairment is associated with an increased risk of stroke in patients with AF
Which one of these statements is false?
- Recurrent AF describes repeated episodes of arrhythmia
- Recurrent AF may be paroxysmal or persistent
- Permanent AF includes arrhythmia despite attempted cardioversion
- Paroxysmal AF episodes terminate spontaneously within three days
Considering the management of AF, which one of these statements is false?
- It is often symptom-led
- Fewer than 1 in 10 patients presenting with acute AF revert spontaneously to sinus rhythm within 48 hours
- Patients with acute-onset AF and haemodynamic compromise should be referred for urgent cardioversion
- The optimal strategy for haemodynamically stable patients depends partly on extracardiac pathology
Which one of these statements about the drug treatment of AF is false?
- In persistent AF, pharmacological cardioversion is usually achieved by class 1c or class III antiarrhythmic drugs
- Beta-blockers are the drugs of first choice for prevention of AF relapses
- With optimal management to maintain sinus rhythm, 90 per cent of patients are free of AF relapses at 12 months
- The use of class 1c antiarrhythmic drugs should be restricted to patients without structural heart disease
Considering antiarrhythmic drugs used to treat AF, which one of these statements is false?
- Flecainide is a class III antiarrhythmic
- A CYP4502D6 inhibitor may cause cardiotoxicity if co-administered with flecainide or propafenone
- Quinidine potentiates the anticoagulant effect of warfarin
- Amiodarone is a rate control agent of choice for patients with COPD or bronchospasm unless they have underlying interstitial disease
Which one of these statements is false?
- Dronedarone is licensed for the prevention of AF recurrences
- The ANDROMEDA trial showed that dronedarone halved mortality in patients with decompensated congestive heart failure
- Dronedarone is less effective than amiodarone in preventing AF recurrences but has fewer side effects
- In the ATHENA trial, dronedarone significantly reduced the composite endpoint of first hospitalisation due to cardiovascular events or death, but not all-cause death
One of these statements is false – which one?
- Large randomised trials show that a rate-control strategy is noninferior to a rhythm-control approach for mortality
- Digoxin reduces mortality and admissions in patients with AF and stable chronic heart failure
- Compared with a rate-control strategy, a rhythm-control strategy is associated with more thromboembolism
- In patients with heart failure, or after myocardial infarction, amiodarone is contraindicated due to its negative inotropic effects
Which one of these statements about thromboprophylaxis in patients with AF is false?
- Adequate antithrombotic therapy with an adjusted dose of warfarin (INR 2–3) significantly reduces all-cause mortality
- Compared with aspirin, warfarin is associated with a higher rate of major bleeding in older people
- Most patients don’t receive the optimal dose of warfarin because of drug interactions and bleeding complications
- According to new European Society of Cardiology guidelines, oral anticoagulation or aspirin may be used in patients with a CHA₂DS₂-VASc score of 1, though oral anticoagulation is preferred

Escriber.com - Home of Wiley interface

Wiley-Blackwell Titles

Advertising and Sponsorship

Search the Site